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TMC8 Antikörper (Center)

TMC8 Reaktivität: Human, Maus, Ratte WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN499810
  • Target Alle TMC8 Antikörper anzeigen
    TMC8 (Transmembrane Channel-Like 8 (TMC8))
    Bindungsspezifität
    • 15
    • 7
    • 7
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Center
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 42
    Kaninchen
    Klonalität
    • 42
    Polyklonal
    Konjugat
    • 11
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TMC8 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 20
    • 13
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody reacts to EVER2.
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    EVER2 antibody was raised against a 14 amino acid peptide from near the center of human EVER2.
    Isotyp
    IgG
    Top Product
    Discover our top product TMC8 Primärantikörper
  • Applikationshinweise
    ELISA. Western Blt: 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    TMC8 (Transmembrane Channel-Like 8 (TMC8))
    Andere Bezeichnung
    TMC8 (TMC8 Produkte)
    Synonyme
    EV2 antikoerper, EVER2 antikoerper, EVIN2 antikoerper, Ever2 antikoerper, mFLJ00400 antikoerper, transmembrane channel like 8 antikoerper, transmembrane channel-like 8 antikoerper, transmembrane channel-like gene family 8 antikoerper, TMC8 antikoerper, Tmc8 antikoerper
    Hintergrund
    Epidermodysplasia verruciformis (EV) is an autosomal recessive genodermatosis associated with a high risk of skin cancers resulting from a high susceptibility to infection by specific human papillomaviruses. Mutations in two homologous genes EVER1 and EVER2 cause the majority of EV cases. These two proteins form a complex and interact with the zinc transporter ZnT-1 in the endoplasmic reticulum. Cells lacking EVER2 accumulated higher levels of zinc in the nucleolus and nucleus compare to those cells with and intact EVER2 gene, indicating that one role of EVER2 is to regulate the intracellular distribution of zinc. At least three isoforms of EVER2 are known to exist, this antibody will only recognize the larger isoform. EVER2 has no cross-reactivity to EVER1.Synonyms: EVER2, EVIN2, Epidermodysplasia verruciformis protein 2, Transmembrane channel-like protein 8
    Gen-ID
    147138
    UniProt
    Q8IU68
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