Cortactin Antikörper (N-Term)

Produktnummer ABIN2774002

Produktdetails anti-Cortactin Antikörper

Target: Cortactin (CTTN)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cortactin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KSAVGFDYQG KTEKHESQRD YSKGFGGKYG IDKDKVDKSA VGFEYQGKTE

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against CTTN. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CTTN

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Cortactin

Target: Cortactin (CTTN)

Andere Bezeichnung: CTTN (CTTN Produkte)

Synonyme: EMS1 antikoerper, 1110020L01Rik antikoerper, Ems1 antikoerper, Cttnb antikoerper, CG3637 antikoerper, Dmel\CG3637 antikoerper, cortactin antikoerper, cttn antikoerper, CTTN1 antikoerper, P85.25 antikoerper, Cttn antikoerper, ems1 antikoerper, CTTN antikoerper, cortactin antikoerper, CG3637 gene product from transcript CG3637-RD antikoerper, cortactin S homeolog antikoerper, cortactin L homeolog antikoerper, src substrate cortactin antikoerper, Src substrate cortactin antikoerper, CTTN antikoerper, Cttn antikoerper, Cortactin antikoerper, cttn.S antikoerper, cttn.L antikoerper, cttn antikoerper, CpipJ_CPIJ006351 antikoerper, Bm1_57220 antikoerper, LOC100533277 antikoerper

Hintergrund: This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.
Alias Symbols: EMS1
Protein Interaction Partner: SPRR2A, CDC37, CTTN, UBC, NEDD8, RPA3, RPA2, RPA1, VTA1, GSPT2, ATG7, UGDH, ME1, IDE, GSPT1, GARS, CTNNA1, ATP6V1C1, APEH, STAT1, SSB, SNX2, SNX1, SHMT2, SHMT1, SARS, RDX, ACTR2, NPM1, LMNA, ACTG1, ACTR3, PAN2, ATF2, DNM2, NCF1, Mbp, ASAP1, CORO1B, SDHAF2
Protein Size: 634

Molekulargewicht: 69 kDa

Gen-ID: 2017

NCBI Accession: NM_138565, NP_612632

Pathways: MAPK Signalweg