Liver Arginase Antikörper (N-Term)
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- Target Alle Liver Arginase (ARG1) Antikörper anzeigen
- Liver Arginase (ARG1) (Arginase, Liver (ARG1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Ratte, Maus, Kaninchen, Rind (Kuh), Hund, Schwein, Pferd, Ziege, Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Liver Arginase Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- HSLAIGSISG HARVHPDLGV IWVDAHTDIN TPLTTTSGNL HGQPVSFLLK
- Kreuzreaktivität
- Rind (Kuh), Hund, Human, Maus, Schwein, Kaninchen, Ratte (Rattus)
- Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against ARG1. It was validated on Western Blot and immunohistochemistry.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human ARG1
- Top Product
- Discover our top product ARG1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 322 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).
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Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).
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- Target
- Liver Arginase (ARG1) (Arginase, Liver (ARG1))
- Andere Bezeichnung
- Arginase-1 (ARG1 Produkte)
- Synonyme
- SI:zC146F4.4 (novel protein with NUDIX domain) antikoerper, si:ch211-146f4.3 antikoerper, argi1 antikoerper, AI antikoerper, AI256583 antikoerper, Arg-1 antikoerper, PGIF antikoerper, arginase 1 antikoerper, arginase antikoerper, Arginase-1 antikoerper, arginase, liver antikoerper, L-arginase antikoerper, arg1 antikoerper, PGTG_16455 antikoerper, argi1 antikoerper, ARG1 antikoerper, Arg1 antikoerper
- Hintergrund
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Arginase catalyzes the hydrolysis of arginine to ornithine and urea. The type I isoform of ARG1, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.
Protein Interaction Partner: RPA3, RPA2, RPA1, SUZ12, EZH2, BMI1, ALDH4A1, ESR1, RAD21, UBC, UCHL5, ATG101, USP53, FLOT1, NOS1, ARG2,
Protein Size: 322 - Molekulargewicht
- 35 kDa
- Gen-ID
- 383
- NCBI Accession
- NM_000045, NP_000036
- UniProt
- P05089
- Pathways
- Cellular Response to Molecule of Bacterial Origin
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