Liver Arginase Antikörper (AA 11-97)

Produktnummer ABIN6939857

Produktdetails anti-Liver Arginase Antikörper

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Bindungsspezifität: AA 11-97

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Liver Arginase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)

Spezifität: Recognizes a protein of 35-38 kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant human ARG1 protein fragment (around aa11-97) (exact sequence is proprietary)

Klon: ARG1-1125

Isotyp: IgG3 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: 293T cells. Hepatocellular Carcinoma (HCC).

Known Application: Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (2-4 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Liver Arginase

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Andere Bezeichnung: ARG1 (ARG1 Produkte)

Synonyme: SI:zC146F4.4 (novel protein with NUDIX domain) antikoerper, si:ch211-146f4.3 antikoerper, argi1 antikoerper, AI antikoerper, AI256583 antikoerper, Arg-1 antikoerper, PGIF antikoerper, arginase 1 antikoerper, arginase antikoerper, Arginase-1 antikoerper, arginase, liver antikoerper, L-arginase antikoerper, arg1 antikoerper, PGTG_16455 antikoerper, argi1 antikoerper, ARG1 antikoerper, Arg1 antikoerper

Molekulargewicht: 35-38kDa

Gen-ID: 383

UniProt: P05089

Pathways: Cellular Response to Molecule of Bacterial Origin