Orf1 (AA 60-240) Antikörper (Biotin)

Produktnummer ABIN2754621

Produktdetails

Target: Orf1

Bindungsspezifität: AA 60-240

Reaktivität: Hepatitis E Virus (HEV)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Biotin

Applikation: ELISA

Kreuzreaktivität: Hepatitis E Virus (HEV)

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Hepatitis E virus genotype 1 Non-structural polyprotein pORF1 protein (60-240AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Antigendetails

Target: Orf1

Substanzklasse: Viral Protein

Hintergrund:

Background: Methyltransferase displays a cytoplasmic capping enzyme activity. This function is necessary since all viral RNAs are synthesized in the cytoplasm, and host capping enzymes are restricted to the nucleus. The enzymatic reaction involves a covalent link between 7-methyl-GMP and the methyltransferase, whereas eukaryotic capping enzymes form a covalent complex only with GMP. Methyltransferase catalyzes transfer of a methyl group from S-adenosylmethionine to GTP and GDP to yield m7GTP or m7GDP. GMP, GpppG, and GpppA were poor substrates for the methyltransferase. This enzyme also displays guanylyltransferase activity to form a covalent complex, methyltransferase-m7GMP, from which 7-methyl-GMP is transferred to the mRNA to create the cap structure. Cap analogs such as m7GTP, m7GDP, et2m7GMP, and m2et7GMP inhibit the methyltransferase reaction (By similarity).

Aliases: ORF1 antibody, Non-structural polyprotein pORF1 [Includes: Methyltransferase antibody, EC 2.1.1.- antibody, EC 2.7.7.-), Putative papain-like cysteine protease antibody, PLP antibody, EC 3.4.22.-), NTPase/helicase antibody, EC 3.6.4.-), RNA-directed RNA polymerase antibody, RdRp antibody, EC 2.7.7.48)] antibody

UniProt: P33424