CARD11 Antikörper (N-Term)

Produktnummer ABIN2745520

Produktdetails anti-CARD11 Antikörper

Target: CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))

Bindungsspezifität: AA 1-221, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CARD11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Spezifität: Recognizes human and mouse CARMA1. Detects a band of ~130Dka by Western blot.

Kreuzreaktivität: Human, Maus

Immunogen: N-terminal human CARMA1 (aa 1-221 containing the CARD domain).

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: In PBS containing 10 % glycerol and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Haltbarkeit: 12 months

Details zu CARD11

Target: CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))

Andere Bezeichnung: CARMA1 (CARD11 Produkte)

Synonyme: BENTA antikoerper, BIMP3 antikoerper, CARMA1 antikoerper, PPBL antikoerper, 0610008L17Rik antikoerper, 2410011D02Rik antikoerper, CARD11 antikoerper, LOC100232755 antikoerper, caspase recruitment domain family member 11 antikoerper, caspase recruitment domain family, member 11 antikoerper, caspase recruitment domain-containing protein 11 antikoerper, CARD11 antikoerper, Card11 antikoerper, LOC100550812 antikoerper, card11 antikoerper

Hintergrund: CARMA1 is involved in the costimulatory signal essential for T cell receptor (TCR)-mediated T cell activation. Its binding to DPP4 induces T cell proliferation and NF-kappaB activation in a T cell receptor/CD3-dependent manner. CARMA1 activates NF-kappaB via Bcl10 and IKK.

UniProt: Q9BXL7

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, BCR Signaling