Thyroglobulin Antikörper

Produktnummer ABIN2744777

Produktdetails anti-Thyroglobulin Antikörper

Target: Thyroglobulin (TG)

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Thyroglobulin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Human TG / Thyroglobulin

Aufreinigung: Protein G purified

Immunogen: Human thyroid follicular cells were used as the immunogen for this Thyroglobulin antibody.

Type of Immunogen: Cells

Klon: 6E1 or TGB05

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Approved: ELISA, Flo (0.5 - 1 μg/10 x10⁶), IHC, IHC-P (0.5 - 1 μg/mL), WB (0.5 - 1 μg/mL)

Usage: Thyroglobulin is a 660  kDa dimeric pre-protein with mutiple glycosylation sites, detected at ~300  kDa in western blot. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for thyroglobulin antibody even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently thyroglobulin antibody negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Thyroglobulin antibody, combined with calcitonin antibody, can identify medullary carcinomas of the thyroid. Furthermore, thyroglobulin antibody, combined with TTF1 antibody, can be a reliable marker to differentiate between primary thyroid and lung neoplasms. ELISA: Order BSA-free format for coating.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2°C to 8°C.

Details zu Thyroglobulin

Target: Thyroglobulin (TG)

Andere Bezeichnung: TG / Thyroglobulin (TG Produkte)

Synonyme: TG antikoerper, cb717 antikoerper, AITD3 antikoerper, TGN antikoerper, Tgn antikoerper, cog antikoerper, thyroglobulin antikoerper, TG antikoerper, tg antikoerper, LOC701526 antikoerper, LOC701756 antikoerper, LOC100434297 antikoerper, Tg antikoerper

Hintergrund: Name/Gene ID: TG

Synonyms: TG, AITD3, TDH3, Thyroglobulin, TGN

Gen-ID: 7038

Pathways: Thyroid Hormone Synthesis