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Rekombinanter Thyroglobulin Antikörper

TG Reaktivität: Human IHC, StM Wirt: Maus Monoclonal r6E1 unconjugated Recombinant Antibody
Produktnummer ABIN6940712
  • Target Alle Thyroglobulin (TG) Antikörper anzeigen
    Thyroglobulin (TG)
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    • 103
    • 36
    • 36
    • 2
    • 1
    Human
    Wirt
    • 57
    • 43
    • 5
    • 4
    • 1
    • 1
    Maus
    Klonalität
    • 64
    • 44
    Monoklonal
    Konjugat
    • 68
    • 12
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Thyroglobulin Antikörper ist unkonjugiert
    Applikation
    • 39
    • 37
    • 31
    • 27
    • 18
    • 16
    • 11
    • 11
    • 10
    • 9
    • 8
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Keine Kreuzreaktivität
    Maus, Ratte (Rattus)
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Human thyroid follicular cells
    Klon
    R6E1
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product TG Primärantikörper
  • Applikationshinweise

    Positive Control: Thyroid.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL, 30 min at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    Thyroglobulin (TG)
    Andere Bezeichnung
    Thyroglobulin (Thyroidal Cell Marker) (TG Produkte)
    Synonyme
    TG antikoerper, cb717 antikoerper, AITD3 antikoerper, TGN antikoerper, Tgn antikoerper, cog antikoerper, thyroglobulin antikoerper, TG antikoerper, tg antikoerper, LOC701526 antikoerper, LOC701756 antikoerper, LOC100434297 antikoerper, Tg antikoerper
    Hintergrund
    Thyroglobulin is a 660 kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms.
    Molekulargewicht
    660kDa (Dimeric Form)
    Gen-ID
    7038
    UniProt
    P01266
    Pathways
    Thyroid Hormone Synthesis
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