NDUFA5 Antikörper (AA 3-116)

Produktnummer ABIN2726996

Produktdetails anti-NDUFA5 Antikörper

Target: NDUFA5 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 5, 13kDa (NDUFA5))

Bindungsspezifität: AA 3-116

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NDUFA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktmerkmale: Homo sapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13 kDa (NDUFA5), nuclear gene encoding mitochondrial protein

Aufreinigung: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Human recombinant protein fragment corresponding to amino acids 3-116 of human NDUFA5(NP_004991) produced in HEK293T cell.

Klon: 1E8

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB 1:2000, IF 1:100,

Kommentare:

The concentration of the product may vary between diferrent lots.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu NDUFA5

Target: NDUFA5 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 5, 13kDa (NDUFA5))

Andere Bezeichnung: NDUFA5 (NDUFA5 Produkte)

Synonyme: NADHUO antikoerper, B13 antikoerper, CI-13KD-B antikoerper, CI-13kB antikoerper, NUFM antikoerper, UQOR13 antikoerper, 2900002J19Rik antikoerper, NADH:ubiquinone oxidoreductase subunit A5 antikoerper, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 antikoerper, Ndufa5 antikoerper, NDUFA5 antikoerper

Hintergrund: The human NDUFA5 gene codes for the B13 subunit of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. The high degree of conservation of NDUFA5 extending to plants and fungi indicates its functional significance in the enzyme complex. The protein localizes to the inner mitochondrial membrane as part of the 7 component-containing, water soluble 'iron-sulfur protein' (IP) fraction of complex I, although its specific role is unknown. It is assumed to undergo post-translational removal of the initiator methionine and N-acetylation of the next amino acid. The predicted secondary structure is primarily alpha helix, but the carboxy-terminal half of the protein has high potential to adopt a coiled-coil form. The amino-terminal part contains a putative beta sheet rich in hydrophobic amino acids that may serve as mitochondrial import signal. Related pseudogenes have also been identified on four other chromosomes.

Molekulargewicht: 13.3 kDa

Gen-ID: 4698

NCBI Accession: NM_005000

HGNC: 4698