Activin A Receptor Type IB/ALK-4 Antikörper

Produktnummer ABIN272185

Produktdetails anti-Activin A Receptor Type IB/ALK-4 Antikörper

Target: Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Activin A Receptor Type IB/ALK-4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of ACTR-IB protein. (region surrounding Gly111)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu Activin A Receptor Type IB/ALK-4

Target: Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))

Andere Bezeichnung: Activin Receptor Type 1B (ACVR1B) (ACVR1B Produkte)

Synonyme: ACVR1B antikoerper, alk4 antikoerper, skr2 antikoerper, alk-4 antikoerper, xalk4 antikoerper, actrib antikoerper, acvrlk4 antikoerper, DKFZp469A1614 antikoerper, 6820432J04 antikoerper, ActR-IB antikoerper, ActRIB antikoerper, Acvrlk4 antikoerper, Alk4 antikoerper, SKR2 antikoerper, ACTRIB antikoerper, ACVRLK4 antikoerper, ALK4 antikoerper, Skr2 antikoerper, axis antikoerper, taram-a antikoerper, tarama antikoerper, wu:fb75f01 antikoerper, activin A receptor type 1B antikoerper, Activin receptor type-1B antikoerper, activin A receptor, type IB antikoerper, activin A receptor, type 1B antikoerper, activin A receptor type 1Ba antikoerper, ACVR1B antikoerper, acvr1b antikoerper, acv1b antikoerper, Acvr1b antikoerper, acvr1ba antikoerper

Hintergrund: Members of the transforming growth factor β superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex. Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR-IA (also designated ACVRI and ALK-2) or ACTR-IB (also designated ALK-4 and SKR2), and a type II receptor, ACTR-IIA (also designated ACVR2A) or ACTR-IIB (also designated ACVR2B). Both receptor types are highly expressed in brain. The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morpho genesis in a dose dependent fashion.Synonyms: ACTR-IB, ACVRLK4, ALK4, Activin receptor type IB, Activin receptor-like kinase 4, SKR2, Serine/threonine-protein kinase receptor R2

Molekulargewicht: approx. 56 kDa

Gen-ID: 91

NCBI Accession: NP_004293

UniProt: P36896