AFT7 Antikörper

Produktnummer ABIN272174

Produktdetails anti-AFT7 Antikörper

Target: AFT7 (Activating Transcription Factor 7 (AFT7))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AFT7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of ATF-7 protein. (region surrounding Phe74)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu AFT7

Target: AFT7 (Activating Transcription Factor 7 (AFT7))

Andere Bezeichnung: ATF7 (AFT7 Produkte)

Synonyme: ATFA antikoerper, 1110012F10Rik antikoerper, 9430065F09Rik antikoerper, AI549878 antikoerper, C130020M04Rik antikoerper, ATF7 antikoerper, fa97a09 antikoerper, fc25b12 antikoerper, wu:fa97a09 antikoerper, wu:fc25b12 antikoerper, atfa antikoerper, activating transcription factor 7 antikoerper, activating transcription factor 7b antikoerper, ATF7 antikoerper, Atf7 antikoerper, atf7b antikoerper, atf7 antikoerper

Hintergrund: Eukaryotic gene transcription is regulated by sequence-specific transcription factors, which bind modular cis acting promoter and enhancer elements. The cAMP response element (CRE) consists of the palindromic octanucleotide TGACGTCA. There are several CRE binding proteins within the ATF/CREB family, including CREB-1, CREB-2 (also designated ATF-4), ATF-1, ATF-2 and ATF-3. A novel basic leucine zipper (bZIP) protein, designated ATF-7, is closely related to members of the ATF/CREB family of bZIP proteins, with highest homology to ATF-4. ATF-7 physically interacts with the PRL-1 protein-tyrosine phosphatase (PTPase), which is a predominately nuclear, farnesylated PTPase. ATF-7 homodimers bind specifically to CRE elements. ATF-7 is expressed in a number of different tissues and is expressed in association with differentiation. ATF-7 and PRL-1 interact with each other through the bZIP region of ATF-7 and the phosphatase domain of PRL-1. In addition, PRL-1 is able to dephosphorylate ATF-7 in vitro.Synonyms: ATF-7, ATF-A, ATFA, Activating transcription factor 7, Cyclic AMP-dependent transcription factor ATF-7, cAMP-dependent transcription factor ATF-7

Molekulargewicht: approx. 35, 53 kDa

Gen-ID: 11016

NCBI Accession: NP_001123531

UniProt: P17544