AFT7 Antikörper (AA 1-117)

Produktnummer ABIN7148809

Produktdetails anti-AFT7 Antikörper

Target: AFT7 (Activating Transcription Factor 7 (AFT7))

Bindungsspezifität: AA 1-117

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AFT7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Cyclic AMP-dependent transcription factor ATF-7 protein (1-117AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu AFT7

Target: AFT7 (Activating Transcription Factor 7 (AFT7))

Andere Bezeichnung: ATF7 (AFT7 Produkte)

Synonyme: ATFA antikoerper, 1110012F10Rik antikoerper, 9430065F09Rik antikoerper, AI549878 antikoerper, C130020M04Rik antikoerper, ATF7 antikoerper, fa97a09 antikoerper, fc25b12 antikoerper, wu:fa97a09 antikoerper, wu:fc25b12 antikoerper, atfa antikoerper, activating transcription factor 7 antikoerper, activating transcription factor 7b antikoerper, ATF7 antikoerper, Atf7 antikoerper, atf7b antikoerper, atf7 antikoerper

Hintergrund:

Background: Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5\\\'-GTGACGT[AG][AG]-3\\\'), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family. Isoform 4/ATF-A0 acts as a dominant repressor of the E-selectin/NF-ELAM1/delta-A promoter. Isoform 5/ATF-4 acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation.

Aliases: 1110012F10Rik antibody, 9430065F09Rik antibody, Activating transcription factor 7 antibody, AI549878 antibody, ATF7 antibody, Atf7 protein antibody, ATF7_HUMAN antibody, ATFA antibody, C130020M04Rik antibody, cAMP-dependent transcription factor ATF-7 antibody, Cyclic AMP-dependent transcription factor ATF 7 antibody, Cyclic AMP-dependent transcription factor ATF-7 antibody, MGC31554 antibody, MGC57182 antibody, Transcription factor ATF A antibody, Transcription factor ATF-A antibody

UniProt: P17544