RPS6 Antikörper

Produktnummer ABIN272077

Produktdetails anti-RPS6 Antikörper

Target: RPS6 (Ribosomal Protein S6 (RPS6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPS6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of RS6 protein. (region surrounding Leu234)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 1000approx. 1: 5000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IF: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu RPS6

Target: RPS6 (Ribosomal Protein S6 (RPS6))

Andere Bezeichnung: RPS6 (RPS6 Produkte)

Synonyme: S6 antikoerper, rps6 antikoerper, rps6a antikoerper, S6R antikoerper, (Rp)S6 antikoerper, CG10944 antikoerper, DS6 antikoerper, Dmel\\CG10944 antikoerper, M(1)7BC antikoerper, M(1)7C antikoerper, RPS6 antikoerper, Rp S6 antikoerper, Rps6 antikoerper, air8 antikoerper, air[8] antikoerper, anon-WO02059370.61 antikoerper, hen antikoerper, l(1)air8 antikoerper, l(1)air[8] antikoerper, l(1)hen antikoerper, pp30 antikoerper, rpS6 antikoerper, wu:fa92e06 antikoerper, wu:fb64g06 antikoerper, zgc:92237 antikoerper, ribosomal protein S6 antikoerper, ribosomal protein S6 S homeolog antikoerper, S6 ribosomal protein antikoerper, Ribosomal protein S6 antikoerper, 30S ribosomal protein S6 antikoerper, 40S ribosomal protein S6 antikoerper, RPS6 antikoerper, rps6.S antikoerper, LOC100135859 antikoerper, Rps6 antikoerper, RpS6 antikoerper, rps6 antikoerper, rps-6 antikoerper, LOC100533219 antikoerper

Hintergrund: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.Synonyms: 40S ribosomal protein S6, Phosphoprotein NP33

Molekulargewicht: approx. 32 kDa

Gen-ID: 6194

NCBI Accession: NP_001001

UniProt: P62753

Pathways: Carbohydrate Homeostasis, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly