RPS6 Antikörper (AA 227-257)

Produktnummer ABIN954620

Der Kaninchen Polyklonal anti-RPS6 Antikörper wird verwendet zum Nachweis von RPS6 in Proben von Human und Maus. Er wurde validiert für WB, IHC (p), FACS und EIA.

Kurzübersicht für RPS6 Antikörper (AA 227-257) (ABIN954620)

Target: RPS6 (Ribosomal Protein S6 (RPS6))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPS6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Produktdetails anti-RPS6 Antikörper

Bindungsspezifität: AA 227-257

Spezifität: Recognizes RPS6 (Ser240/244).

Aufreinigung: Protein A column followed by peptide Affinity purification

Immunogen: KLH conjugated synthetic peptide between 227-257 amino acids from Human RPS6. Genename: RPS6

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu RPS6

Target: RPS6 (Ribosomal Protein S6 (RPS6))

Andere Bezeichnung: RPS6

Hintergrund: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.Synonyms: 40S ribosomal protein S6, Phosphoprotein NP33

Gen-ID: 6194

NCBI Accession: NP_001001

Pathways: Carbohydrate Homeostasis, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly