ETS1 Antikörper

Produktnummer ABIN272023

Produktdetails anti-ETS1 Antikörper

Target: ETS1 (V-Ets erythroblastosis Virus E26 Oncogene Homolog 1 (Avian) (ETS1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ETS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of ETS1 protein. (region surrounding Ala32)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 1000approx. 1: 5000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IF: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu ETS1

Target: ETS1 (V-Ets erythroblastosis Virus E26 Oncogene Homolog 1 (Avian) (ETS1))

Andere Bezeichnung: ETS1 (ETS1 Produkte)

Synonyme: ETS-1 antikoerper, EWSR2 antikoerper, ets1a-a antikoerper, XE1-a antikoerper, X1-c-ets-1a antikoerper, ETS-1A antikoerper, ETS-1B antikoerper, TNIP1 antikoerper, c-ets-1 antikoerper, c-ets1 antikoerper, Ets-1 antikoerper, Etsoncb antikoerper, Tpl1 antikoerper, ets1 antikoerper, ets antikoerper, AI196000 antikoerper, AI448617 antikoerper, D230050P06 antikoerper, cb516 antikoerper, id:ibd1116 antikoerper, zgc:110573 antikoerper, XE1-b antikoerper, ets-1 antikoerper, ets1-B antikoerper, ETS proto-oncogene 1, transcription factor antikoerper, v-ets avian erythroblastosis virus E26 oncogene homolog 1 S homeolog antikoerper, v-ets avian erythroblastosis virus E26 oncogene homolog 1 antikoerper, v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) antikoerper, E26 avian leukemia oncogene 1, 5' domain antikoerper, v-ets avian erythroblastosis virus E26 oncogene homolog 1 L homeolog antikoerper, ETS1 antikoerper, ets1.S antikoerper, Ets1 antikoerper, ets1 antikoerper, ets1.L antikoerper

Hintergrund: Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. This family of genes currently includes Ets-1, Ets-2, Erg-1-3, Elk-1, Elf-1, Elf-5, NERF, PU.1, PEA3, ERM, FEV, ER8l, Fli-1, TEL, Spi-B, ESE-1, ESE-3A, Net, ABT1 and ERF. Members of the Ets gene family exhibit varied patterns of tissue expression and share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. This conserved domain is essential for Ets-1 binding to DNA and is likely to be responsible for the DNA binding activity of all members of the Ets gene family. Several of these proteins have been shown to recognize similar motifs in DNA that share a centrally located 5'-GGAA-3' element. Evidence indicates that the DNA binding activity by Ets-1 is regulated at the level of phosphorylation.Synonyms: EWSR2, Protein C-ets-1, p54

Molekulargewicht: approx. 54 kDa

Gen-ID: 2113

NCBI Accession: NP_005229

UniProt: P14921