Transglutaminase 2 Antikörper

Produktnummer ABIN271855

Produktdetails anti-Transglutaminase 2 Antikörper

Target: Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Transglutaminase 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of Transglutaminase 2 protein. (region surrounding Asp11)

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu Transglutaminase 2

Target: Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))

Andere Bezeichnung: Transglutaminase-2 (TGM2) (TGM2 Produkte)

Synonyme: G-ALPHA-h antikoerper, GNAH antikoerper, TG2 antikoerper, TGC antikoerper, tgm2 antikoerper, zgc:101081 antikoerper, TgaseII antikoerper, TGM2 antikoerper, fc12b04 antikoerper, wu:fc12b04 antikoerper, zgc:136700 antikoerper, TGL2 antikoerper, G[a]h antikoerper, TGase2 antikoerper, tTG antikoerper, tTGas antikoerper, transglutaminase 2 antikoerper, transglutaminase 2, C polypeptide A antikoerper, transglutaminase 2b antikoerper, transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) antikoerper, transglutaminase 2, C polypeptide antikoerper, TGM2 antikoerper, tgm2a antikoerper, Tgm2 antikoerper, tgm2b antikoerper

Hintergrund: Tissue transglutaminase is a calcium activated enzyme which catalyzes the cross linking of proteins and the conjugation of polyamines to proteins. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD). CD, a genetic, immunologically mediated small bowel enteropathy that causes malabsorption, is a relatively common disorder in Western countries.Synonyms: Protein-glutamine gamma-glutamyltransferase 2, TGase C, TGase-H, Tissue transglutaminase

Molekulargewicht: approx. 77 kDa

Gen-ID: 7052

NCBI Accession: NP_004604

UniProt: P21980

Pathways: Tube Formation, Thromboxane A2 Receptor Signaling