SMC1A Antikörper

Produktnummer ABIN271817

Produktdetails anti-SMC1A Antikörper

Target: SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMC1A Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of SMC1 protein. (region surrounding Ser951)

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 10000approx. 1: 20000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu SMC1A

Target: SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))

Andere Bezeichnung: SMC1A / SMC1 (SMC1A Produkte)

Synonyme: CDLS2 antikoerper, DXS423E antikoerper, SB1.8 antikoerper, SMC1 antikoerper, SMC1L1 antikoerper, SMC1alpha antikoerper, SMCB antikoerper, SMC-1A antikoerper, NV15570 antikoerper, 5830426I24Rik antikoerper, Sb1.8 antikoerper, Smc1 antikoerper, Smc1alpha antikoerper, Smc1l1 antikoerper, Smcb antikoerper, mKIAA0178 antikoerper, smc1 antikoerper, smc1a antikoerper, smc1l1 antikoerper, xSMC1 antikoerper, smc1aa antikoerper, structural maintenance of chromosomes 1A antikoerper, structural maintenance of chromosomes 1A b antikoerper, structural maintenance of chromosomes 1A L homeolog antikoerper, SMC1A antikoerper, smc1a antikoerper, Smc1a antikoerper, smc1ab antikoerper, smc1a.L antikoerper

Hintergrund: The SMC (structural maintenance of chromosomes) family of proteins form heterodimeric complexes that modulate sister chromatid cohesion and chromosome condensation for mitosis. The two distinct classes of SMC protein complexes are comprised of SMC1 (also designated SB1.8) with SMC3 (also designated HCAP for human chromosome-associated protein, and Bamacan), and SMC2 (also designated hCAP-E) with SMC4 (also designated hCAP-C). The SMC1/SMC3 complex is required for metaphase progression in mitotic cells and functions independently of the SMC2/SMC4 complex during the cell cycle. SMC1 is ubiqitiously expressed as a 150 kDa protein in various human tissues, including thymus, testis, and colon. SMC3 is expressed as a 146 kDa nuclear protein in the colon, but can also occur as a secreted proteoglycan (called Bamacan) expressed in testis and brain. Bamacan contains several glycosylation sites and is thought to play a role in basement membrane physiology.Synonyms: DXS423E, SB1.8, SMC protein 1A, SMC-1-alpha, SMC-1A, SMC1L1, Structural maintenance of chromosomes protein 1A

Molekulargewicht: approx. 143 kDa

Gen-ID: 8243

NCBI Accession: NP_006297

UniProt: Q14683

Pathways: Stem Cell Maintenance