Oct-2 Antikörper

Produktnummer ABIN271754

Produktdetails anti-Oct-2 Antikörper

Target: Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Oct-2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of OCT2/OTF2 (H3) protein. (region surrounding His3)

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IF: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu Oct-2

Target: Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))

Andere Bezeichnung: POU2F2 / OCT2 (POU2F2 Produkte)

Synonyme: OCT2 antikoerper, OTF2 antikoerper, Oct-2 antikoerper, Pou2f2 antikoerper, Oct2a antikoerper, Oct2b antikoerper, Otf-2 antikoerper, Otf2 antikoerper, 2-Oct antikoerper, Oct2 antikoerper, POU class 2 homeobox 2 antikoerper, POU domain, class 2, transcription factor 2 antikoerper, solute carrier family 22 (organic cation transporter), member 2 antikoerper, POU2F2 antikoerper, Pou2f2 antikoerper, SLC22A2 antikoerper

Hintergrund: Organic cation transporters (OCT) are expressed in the plasma membrane of epithelial cells from a wide range of tissues, where they function in the elimination of ndogenous amines, cationic drugs and other xenobiotics. The structure of OCTs consists of a 12-transmembrane-domain structure and a large extracellular hydrophilic loop. In humans, OCT1 is primarily expressed in the liver while OCT2 is expressed in the kidney. OCT3 is expressed in the placenta, skeletal muscle, prostate, aorta and liver. OCT3, also known as extraneuronal monoamine transporter, is widely expressed in different regions of the brain including the hippocampus, cerebellum and cerebral cortex. OCT3 mediates the uptake of several neuroactive agents, including dopamine, and may play an important role in the disposition of neurotransmitters and cationic neurotoxins in the brain. The genes encoding human OCT1-3 map to a conserved cluster at chromosome 6q26-q27.Synonyms: Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, OTF2, Oct-2, Octamer-binding protein 2, Octamer-binding transcription factor 2, Otf-2, POU domain class 2 transcription factor 2

Molekulargewicht: approx. 52 kDa

Gen-ID: 5452

NCBI Accession: NP_001193954

UniProt: P09086