CD79b Antikörper

Produktnummer ABIN2689399

Produktdetails anti-CD79b Antikörper

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD79b Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Marke: BD Pharmingen™

Produktmerkmale: Immunoglobulin (Ig) antigen receptors are composed of a non-covalently- ssociated complex of Ig and two other proteins, Igα and Igβ, which have been designated in the Fifth International Leukocyte Workshop as CD79a and CD79b respectively. CB3-1 reacts with CD79b, which is expressed on surface Ig(sIg)-positive lymphocytes and B-cell lines but only in the cytoplasm of sIg-negative cells including most terminal deoxynucleotidyl transferase (TdT) positive early pre-B and all cytoplasmic μ positive pre-B cell lines. Antibodies to CD79b are helpful in delineating signal transduction pathways activated via antibody receptors during different stages of B-cell differentiation. Profile of peripheral blood lymphocytes analyzed by flow cytometry

BD Pharmingen™ Purified Mouse Anti-Human CD79b - Purified - Clone CB3-1 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Klon: CB3

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4°C.

Referenzen für anti-CD79b Antikörper (ABIN2689399)

Sanchez, Misulovin, Burkhardt, Mahajan, Costa, Franke, Bolen, Nussenzweig: "Signal transduction by immunoglobulin is mediated through Ig alpha and Ig beta." in: The Journal of experimental medicine, Vol. 178, Issue 3, pp. 1049-55, (1993) (PubMed).

Nakamura, Kubagawa, Cooper: "Heterogeneity of immunoglobulin-associated molecules on human B cells identified by monoclonal antibodies." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 18, pp. 8522-6, (1992) (PubMed).

Details zu CD79b

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Andere Bezeichnung: CD79b (CD79B Produkte)

Synonyme: B29 antikoerper, Ig-beta antikoerper, Igb antikoerper, Igbeta antikoerper, AGM6 antikoerper, IGB antikoerper, CD79B antigen antikoerper, CD79b molecule antikoerper, Cd79b antikoerper, CD79B antikoerper

Hintergrund: Synonyms: Igβ

Pathways: BCR Signaling