IL2 Receptor beta Antikörper (Biotin)

Produktnummer ABIN2688931

Produktdetails anti-IL2 Receptor beta Antikörper (Biotin)

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL2 Receptor beta Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS)

Marke: BD Pharmingen™

Produktmerkmale: The Mik-β3 clone reacts with CD122, the p75 (β chain) of the human high affinity receptor for interleukin 2 (IL-2Rβ), a 70-75 kD type I transmembrane protein expressed on mature T- and pre-B-cell subsets, thymocytes, monocytes, hematopoietic progenitor cells, fetal liver cells and stromal cells. The IL-2Rβ plays a role in B-cell proliferation, T-cell proliferation and activation. Profile of peripheral blood lymphocytes analyzed on a FACScan

BD Pharmingen™ Biotin Mouse Anti-Human CD122 - Biotin - Clone Mik-β3 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.5 mg

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Klon: Mik

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Referenzen für anti-IL2 Receptor beta Antikörper (Biotin) (ABIN2688931)

Ishikawa, Uchiyama, Kamio, Onishi, Kodaka, Okuma: "IL-4 down-regulates IL-2 receptor p75 by accelerating its endocytosis." in: International immunology, Vol. 3, Issue 6, pp. 517-25, (1991) (PubMed).

Tsudo, Kitamura, Miyasaka: "Characterization of the interleukin 2 receptor beta chain using three distinct monoclonal antibodies." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 6, pp. 1982-6, (1989) (PubMed).

Guesdon, Ternynck, Avrameas: "The use of avidin-biotin interaction in immunoenzymatic techniques." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 27, Issue 8, pp. 1131-9, (1979) (PubMed).

Details zu IL2 Receptor beta

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Andere Bezeichnung: CD122 (IL2RB Produkte)

Synonyme: IL2RB antikoerper, il-2rb antikoerper, CD122 antikoerper, IL15RB antikoerper, P70-75 antikoerper, IL2RBC antikoerper, IL-15Rbeta antikoerper, IL15Rbeta antikoerper, Il-2/15Rbeta antikoerper, Il-2Rbeta antikoerper, p70 antikoerper, interleukin 2 receptor subunit beta antikoerper, interleukin-2 receptor subunit beta antikoerper, interleukin 2 receptor, beta antikoerper, interleukin 2 receptor, beta chain antikoerper, IL2RB antikoerper, LOC510185 antikoerper, il2rb antikoerper, Il2rb antikoerper

Hintergrund: Synonyms: IL-2 Receptor β chain, p75

Pathways: JAK-STAT Signalweg, Growth Factor Binding