VISTA Antikörper

Produktnummer ABIN2665323

Produktdetails anti-VISTA Antikörper

Target: VISTA (V-type immunoglobulin domain-containing suppressor of T-cell activation (VISTA))

Reaktivität: Maus

Wirt: Armenischer Hamster

Klonalität: Monoklonal

Konjugat: Dieser VISTA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Aufreinigung: The antibody was purified by affinity chromatography.

Klon: MH5A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu VISTA

Target: VISTA (V-type immunoglobulin domain-containing suppressor of T-cell activation (VISTA))

Andere Bezeichnung: PD-1H (VISTA Produkte)

Synonyme: MGC112715 antikoerper, MGC151567 antikoerper, B7-H5 antikoerper, B7H5 antikoerper, GI24 antikoerper, PP2135 antikoerper, SISP1 antikoerper, Dies1 antikoerper, VISTA antikoerper, V-set immunoregulatory receptor antikoerper, vsir antikoerper, Vsir antikoerper, VSIR antikoerper

Hintergrund: PD-1H, also known as VISTA, is a 309 aa type I transmembrane protein, composed of seven exons. PD-1H has one Ig-V like domain, and its sequence is similar to the Ig-V domains of the members of CD28 and B7 families. PD-1H is expressed by a subset of T cells, macrophages, dendritic cells, neutrophils, and NK cells. It has been proposed that PD-1H can be useful to modulate the host immune response to allogeneic transplants.

Pathways: Cancer Immune Checkpoints