Macrophage Mannose Receptor 1 Antikörper

Produktnummer ABIN2664385

Produktdetails anti-Macrophage Mannose Receptor 1 Antikörper

Target: Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Macrophage Mannose Receptor 1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Cytometry by Time of Flight (CyTOF)

Aufreinigung: The antibody was purified by affinity chromatography.

Klon: 15-2

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu Macrophage Mannose Receptor 1

Target: Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))

Andere Bezeichnung: CD206 (MRC1 Produkte)

Synonyme: CD206 antikoerper, CLEC13D antikoerper, CLEC13DL antikoerper, MMR antikoerper, MRC1L1 antikoerper, bA541I19.1 antikoerper, AW259686 antikoerper, MR antikoerper, mrc1 antikoerper, MGC86525 antikoerper, MRC1 antikoerper, MRC1L-A antikoerper, mannose receptor C-type 1 antikoerper, mannose receptor, C type 1 antikoerper, mannose receptor C-type 1 L homeolog antikoerper, mediator of replication checkpoint 1 antikoerper, MRC1 antikoerper, Mrc1 antikoerper, mrc1.L antikoerper, mrc1 antikoerper

Hintergrund: Macrophage mannose receptor (MMR) is a 162-175 kD type I membrane protein also known as CD206, MRC1, or mannose receptor (MR). It is a pattern recognition receptor (PRR) that belongs to C-type lectin superfamily. MMR is expressed on macrophages, dendritic cells, and hepatic or lymphatic endothelial cells, but not on monocytes. MMR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine. MMR mediates endocytosis and phagocytosis, induces activation of macrophages and antigen presentation, plays an important role in host defense, and provides a link between innate and adaptive immunity.