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CD180 Antikörper

CD180 Reaktivität: Human FACS Wirt: Maus Monoclonal MHR73-11 unconjugated
Produktnummer ABIN2664307
  • Target Alle CD180 Antikörper anzeigen
    CD180 (CD180 Molecule (CD180))
    Reaktivität
    • 18
    • 12
    • 2
    • 1
    Human
    Wirt
    • 11
    • 7
    • 6
    Maus
    Klonalität
    • 13
    • 11
    Monoklonal
    Konjugat
    • 17
    • 3
    • 2
    • 1
    • 1
    Dieser CD180 Antikörper ist unkonjugiert
    Applikation
    • 14
    • 12
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    Flow Cytometry (FACS)
    Kreuzreaktivität
    Pavian, Cynomolgus, Rhesusaffen
    Aufreinigung
    The antibody was purified by affinity chromatography.
    Klon
    MHR73-11
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product CD180 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    CD180 (CD180 Molecule (CD180))
    Andere Bezeichnung
    CD180 (CD180 Produkte)
    Synonyme
    Ly78 antikoerper, CD180 antikoerper, LY64 antikoerper, RP105 antikoerper, F630107B15 antikoerper, CD180 molecule antikoerper, CD180 antigen antikoerper, Cd180 antikoerper, CD180 antikoerper
    Hintergrund
    CD180, also known as RP105, is a 105 kD member of the toll-like receptor (TLR) family and is expressed on most B cells, monocytes/macrophages and dendritic cells. The TLR family's structural characteristics are critically involved in protein-protein signaling interactions leading to the activation of the innate immune system. Additionally, MD-1, a secretory protein, associates with CD180 (RP105) at the cell surface and this complex, in conjunction with TLR4, recognizes bacterial LPS. The human CD180 (RP105) gene maps to 5q12. The MHR73-11 antibody is able to activate B cells and to protect against irradiation- or dexamethasone-induced apoptosis.
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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