CD131 Antikörper

Produktnummer ABIN2664200

Produktdetails anti-CD131 Antikörper

Target: CD131 (CSF2RB) (Colony Stimulating Factor 2 Receptor, Beta (CSF2RB))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD131 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Aufreinigung: The antibody was purified by affinity chromatography.

Klon: 1C1

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu CD131

Target: CD131 (CSF2RB) (Colony Stimulating Factor 2 Receptor, Beta (CSF2RB))

Andere Bezeichnung: CD131 (CSF2RB Produkte)

Synonyme: Csf2rb1 antikoerper, CSF2RB antikoerper, cd131 antikoerper, cdw131 antikoerper, il3rb antikoerper, il5rb antikoerper, il-3rbc antikoerper, CD131 antikoerper, CDw131 antikoerper, IL3RB antikoerper, IL5RB antikoerper, SMDP5 antikoerper, AI848964 antikoerper, AIC2B antikoerper, Bc antikoerper, Csfgmrb antikoerper, Il3r antikoerper, Il3rb antikoerper, Il3rb1 antikoerper, Il5rb antikoerper, colony stimulating factor 2 receptor beta common subunit antikoerper, colony stimulating factor 2 receptor beta common subunit S homeolog antikoerper, cytokine receptor common subunit beta-like antikoerper, colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) antikoerper, CSF2RB antikoerper, Csf2rb antikoerper, csf2rb.S antikoerper, CRCBL antikoerper, csf2rb antikoerper

Hintergrund: CD131, also known as the IL-3R common β subunit (βC), is a 95-120 kD type I transmembrane glycoprotein and belongs to the Ig superfamily. The common β subunit associates with the specific α subunits of IL-3 receptor, IL-5 receptor and GM-CSF receptor to form high affinity receptors for these cytokines. These cytokine receptors are expressed by neutrophils, eosinophils, monocytes, endothelial cells, fibroblasts and hematopoietic progenitor cells and play a crucial role in growth/activation of eosinophils and in the inflammatory response. The 1C1 antibody is a non-blocking antibody.

Pathways: JAK-STAT Signalweg