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IL7R Antikörper

IL7R Reaktivität: Human FACS Wirt: Maus Monoclonal A019D5 unconjugated
Produktnummer ABIN2664190
  • Target Alle IL7R Antikörper anzeigen
    IL7R (Interleukin 7 Receptor (IL7R))
    Reaktivität
    • 122
    • 67
    • 26
    • 7
    • 4
    • 2
    • 1
    Human
    Wirt
    • 81
    • 48
    • 45
    • 1
    • 1
    Maus
    Klonalität
    • 93
    • 81
    • 2
    Monoklonal
    Konjugat
    • 69
    • 13
    • 13
    • 11
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL7R Antikörper ist unkonjugiert
    Applikation
    • 96
    • 84
    • 48
    • 26
    • 26
    • 20
    • 14
    • 13
    • 10
    • 8
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Aufreinigung
    The antibody was purified by affinity chromatography.
    Klon
    A019D5
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product IL7R Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    IL7R (Interleukin 7 Receptor (IL7R))
    Andere Bezeichnung
    CD127 (IL7R Produkte)
    Synonyme
    IL7R antikoerper, CD127 antikoerper, IL-7Ralpha antikoerper, CDW127 antikoerper, IL-7R-alpha antikoerper, IL7RA antikoerper, ILRA antikoerper, IL-7RA antikoerper, interleukin 7 receptor antikoerper, IL7R antikoerper, Il7r antikoerper
    Hintergrund
    CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.
    Pathways
    JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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