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LAMP1 Antikörper
LAMP1
Reaktivität: Human
FACS, IHC, IF
Wirt: Maus
Monoclonal
H4A3
unconjugated
Produktnummer ABIN2664126
Produktdetails anti-LAMP1 Antikörper
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Target
Alle LAMP1 Antikörper anzeigen
LAMP1
(Lysosomal-Associated Membrane Protein 1 (LAMP1))
Reaktivität
Alle Reaktivitäten für LAMP1 Antikörper
Human
Wirt
Alle Wirte für LAMP1 Antikörper
Maus
Klonalität
Alle Klonalitäten für LAMP1 Antikörper
Monoklonal
Konjugat
Alle Konjugate für LAMP1 Antikörper
Dieser LAMP1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für LAMP1 Antikörper
Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
Kreuzreaktivität
Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops), Pavian, Schimpanse, Pigtailed Macaque, Rhesusaffen, Green Monkey (Chlorocebus sabaeus)
Aufreinigung
The antibody was purified by affinity chromatography.
Klon
H4A3
Isotyp
IgG1 kappa
Top Product
Discover our top product LAMP1 Primärantikörper
Alternativen
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anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) (AA 301-417) antibody
LAMP1
Reaktivität: Human, Maus, Ratte, Affe
WB, FACS, ELISA, ICC, IHC (p), IHC (fro), IF (p), IF (cc)
Wirt: Kaninchen
Polyclonal
unconjugated
Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
The antibody solution should be stored undiluted between 2°C and 8°C.
Details zu LAMP1
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Target
LAMP1
(Lysosomal-Associated Membrane Protein 1 (LAMP1))
Andere Bezeichnung
CD107a (LAMP1 Produkte )
Synonyme
CD107a antikoerper, LAMPA antikoerper, LGP120 antikoerper, AI196048 antikoerper, Lamp-1 antikoerper, LEP100 antikoerper, LAMP-1 antikoerper, LGP-A antikoerper, Lgpa antikoerper, Lysosome-associated membrane protein 1 antikoerper, cd107a antikoerper, lamp-1 antikoerper, lamp1 antikoerper, lampa antikoerper, lgp120 antikoerper, rexp76 antikoerper, lysosomal associated membrane protein 1 antikoerper, lysosomal-associated membrane protein 1 antikoerper, lysosomal-associated membrane protein 1 L homeolog antikoerper, LAMP1 antikoerper, Lamp1 antikoerper, lamp1.L antikoerper
Hintergrund
CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.
Pathways
Autophagie
Zuletzt angesehen
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