CD137 Antikörper (PE)

Produktnummer ABIN2663015

Produktdetails anti-CD137 Antikörper (PE)

Target: CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))

Reaktivität: Maus

Wirt: Hamster

Klonalität: Monoklonal

Konjugat: Dieser CD137 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP)

Aufreinigung: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Klon: 17B5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu CD137

Target: CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))

Andere Bezeichnung: CD137 (TNFRSF9 Produkte)

Synonyme: TNFRSF9 antikoerper, zgc:136557 antikoerper, 4-1BB antikoerper, CD137 antikoerper, CDw137 antikoerper, ILA antikoerper, A930040I11Rik antikoerper, AA408498 antikoerper, AI325004 antikoerper, Cd137 antikoerper, Ly63 antikoerper, tumor necrosis factor receptor superfamily member 9 antikoerper, TNF receptor superfamily member 9 antikoerper, tumor necrosis factor receptor superfamily, member 9a antikoerper, tumor necrosis factor receptor superfamily, member 9 antikoerper, TNFRSF9 antikoerper, tnfrsf9a antikoerper, Tnfrsf9 antikoerper

Hintergrund: CDw137 is a 39 kD TNF-receptor superfamily member also known as 4-1BB, TNFRSF9, Ly-63, and ILA (Induced by Lymphocyte Activation). CDw137 is expressed as monomers, dimers, and tetramers on activated T and B cells. Interaction of CDw137 with its ligand, 4-1BBL (CDw137L), is important in T-B cell costimulation. The 17B5 antibody has been reported to block 4-1BBL costimulated T cell proliferation.

Pathways: Cancer Immune Checkpoints