CSF2RA Antikörper (PE)

Produktnummer ABIN2662955

Produktdetails anti-CSF2RA Antikörper (PE)

Target: CSF2RA (Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CSF2RA Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)

Aufreinigung: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Klon: 4H1

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu CSF2RA

Target: CSF2RA (Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA))

Andere Bezeichnung: CD116 (CSF2RA Produkte)

Synonyme: CD116 antikoerper, CDw116 antikoerper, CSF2R antikoerper, CSF2RAX antikoerper, CSF2RAY antikoerper, CSF2RX antikoerper, CSF2RY antikoerper, GM-CSF-R-alpha antikoerper, GMCSFR antikoerper, GMR antikoerper, SMDP4 antikoerper, Csfgmra antikoerper, GM-CSF-Ra antikoerper, GM-CSFR antikoerper, colony stimulating factor 2 receptor, alpha antikoerper, colony stimulating factor 2 receptor alpha subunit antikoerper, colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) antikoerper, CSF2RA antikoerper, Csf2ra antikoerper

Hintergrund: CD116 is a 70-85 kD α chain of the GM-CSF receptor. It combines with CDw131 β chain to form the high affinity GM-CSF receptor. A soluble form of CD116, which binds GM-CSF with a relatively low affinity, has been identified. In addition, an alternatively spliced form of CD116 with an altered cytoplasmic tail has been described. CD116 is expressed on various myeloid cells including monocytes, macrophages, neutrophils, eosinophils, dendritic cells and their precursors, fibroblasts, and endothelial cells. CD116 is expressed on myeloid leukemias, osteogenic sarcoma cell lines, osteoblast-like cells and breast and lung carcinoma cell lines.

Pathways: JAK-STAT Signalweg