IL2 Antikörper (Interleukin 2) (FITC)

Details for Product anti-IL2 Antibody No. ABIN2661943, Anbieter: Anmelden zum Anzeigen
Antigen
  • IL2
  • IL-2
  • il2
  • TCGF
  • lymphokine
  • Il-2
  • POIL2
  • interleukin 2
  • interleukin-15
  • IL2
  • il2
  • LOC100303688
  • Il2
Reaktivität
Human
481
247
99
29
17
10
6
6
5
4
3
3
1
1
Wirt
Ratte
314
282
209
18
5
4
4
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser IL2 Antikörper ist konjugiert mit FITC
93
50
49
29
28
18
17
14
12
11
9
8
7
7
7
7
7
7
7
6
6
6
4
4
4
4
4
4
4
3
3
2
2
2
1
1
Applikation
Flow Cytometry (FACS)
469
405
224
93
73
50
49
42
41
40
27
26
15
11
11
8
7
7
5
5
4
3
3
2
2
1
1
1
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
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Klon MQ1-17H12
Isotyp IgG2a kappa
Kreuzreaktivität Schimpanse, Pavian, Cynomolgus, Rhesusaffen, Sooty mangabey (Cercocebus atys)
Reinigung The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
Andere Bezeichnung IL-2 (IL2 Antibody Abstract)
Hintergrund IL-2 is a potent lymphoid cell growth factor which exerts its biological activity primarily on T cells, promoting proliferation and maturation. Additionally, IL-2 has been found to stimulate growth and differentiation of B cells, NK cells, LAK cells, monocytes, and oligodendrocytes.
Pathways JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Protect from prolonged exposure to light. Do not freeze.
Lagerung 4 °C
Informationen zur Lagerung The antibody solution should be stored undiluted between 2°C and 8°C.
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-Interleukin 2 (IL2) antibody (FITC) (ABIN2661943) anti-Interleukin 2 (IL2) antibody (FITC)
Flow Cytometry (FACS) image for anti-Interleukin 2 (IL2) antibody (FITC) (ABIN2661943) anti-Interleukin 2 (IL2) antibody (FITC) (Image 2)
Allgemeine Veröffentlichungen Dzhagalov, Chambon, He: "Regulation of CD8+ T lymphocyte effector function and macrophage inflammatory cytokine production by retinoic acid receptor gamma." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 4, pp. 2113-21, 2007 (PubMed).

Raqib, Ekberg, Sharkar, Bardhan, Zychlinsky, Sansonetti, Andersson: "Apoptosis in acute shigellosis is associated with increased production of Fas/Fas ligand, perforin, caspase-1, and caspase-3 but reduced production of Bcl-2 and interleukin-2." in: Infection and immunity, Vol. 70, Issue 6, pp. 3199-207, 2002 (PubMed).

Prussin, Metcalfe: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." in: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, 1996 (PubMed).

Andersson, Abrams, Björk, Funa, Litton, Agren, Andersson: "Concomitant in vivo production of 19 different cytokines in human tonsils." in: Immunology, Vol. 83, Issue 1, pp. 16-24, 1995 (PubMed).

Fernandez, Andersson, Andersson, Troye-Blomberg: "Cytokine synthesis analyzed at the single-cell level before and after revaccination with tetanus toxoid." in: European journal of immunology, Vol. 24, Issue 8, pp. 1808-15, 1994 (PubMed).

Skansén-Saphir, Andersson, Björk, Andersson: "Lymphokine production induced by streptococcal pyrogenic exotoxin-A is selectively down-regulated by pooled human IgG." in: European journal of immunology, Vol. 24, Issue 4, pp. 916-22, 1994 (PubMed).

Nisticò: "Communications among central nervous system, neuroendocrine and immune systems: interleukin-2." in: Progress in neurobiology, Vol. 40, Issue 4, pp. 463-75, 1993 (PubMed).

Taniguchi, Minami: "The IL-2/IL-2 receptor system: a current overview." in: Cell, Vol. 73, Issue 1, pp. 5-8, 1993 (PubMed).

Waldmann, Goldman, Top, Grant, Burton, Bamford, Roessler, Horak, Zaknoen, Kasten-Sportes: "The interleukin-2 receptor: a target for immunotherapy." in: Annals of the New York Academy of Sciences, Vol. 685, pp. 603-10, 1993 (PubMed).

Abrams, Roncarolo, Yssel, Andersson, Gleich, Silver: "Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples." in: Immunological reviews, Vol. 127, Issue 9-10, pp. 5-24, 1992 (PubMed).

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