KIR3DL1 Antikörper (PE-Cy7)

Produktnummer ABIN2659118

Produktdetails anti-KIR3DL1 Antikörper (PE-Cy7)

Target: KIR3DL1 (Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 1 (KIR3DL1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KIR3DL1 Antikörper ist konjugiert mit PE-Cy7

Applikation: Flow Cytometry (FACS)

Aufreinigung: The antibody was purified by affinity chromatography and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.

Klon: DX9

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu KIR3DL1

Target: KIR3DL1 (Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 1 (KIR3DL1))

Andere Bezeichnung: CD158e1 (KIR3DL1 Produkte)

Synonyme: KIR3DL1 antikoerper, KIR3DL3 antikoerper, CD158E1 antikoerper, KIR antikoerper, KIR3DL1/S1 antikoerper, NKAT3 antikoerper, NKB1 antikoerper, NKB1B antikoerper, Kirl1 antikoerper, Kirl2 antikoerper, Krl1 antikoerper, killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 antikoerper, uncharacterized LOC100437736 antikoerper, killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1 antikoerper, KIR3DL1 antikoerper, LOC100437736 antikoerper, Kir3dl1 antikoerper

Hintergrund: CD158e1, also known as NKB1, is a 70 kD member of the immunoglobulin superfamily that is expressed on a subset of natural killer cells and T cells at varying levels among individuals. NKB1 is a type I membrane protein containing two immunoglobulin C2-type domains. The interaction of NKB1 with specific HLA-B antigens on a target cell (the HLA-Bw4 allele, for example) inhibits cytotoxicity and prevents target cell lysis and death. The interactions between KIR and MHC class I are thought to be important in NK and T cell regulation following antigen stimulation. The absence of ligands for KIRs may lower the threshold for activation through activating receptors and increase inflammation and susceptibility to autoimmune disease.