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KIR3DL1 Antikörper (AA 22-340)

KIR3DL1 Reaktivität: Human, Ratte, Affe WB, ELISA, IHC, FACS, ICC, Neut Wirt: Maus Monoclonal 6D9F6 unconjugated
Produktnummer ABIN5611328
  • Target Alle KIR3DL1 Antikörper anzeigen
    KIR3DL1 (Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 1 (KIR3DL1))
    Bindungsspezifität
    • 11
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-340
    Reaktivität
    Human, Ratte, Affe
    Wirt
    • 46
    • 19
    Maus
    Klonalität
    • 46
    • 19
    Monoklonal
    Konjugat
    • 26
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KIR3DL1 Antikörper ist unkonjugiert
    Applikation
    • 46
    • 17
    • 17
    • 12
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human KIR3DL1 (AA: extra 22-340) expressed in Hek293 cells.
    Klon
    6D9F6
    Isotyp
    IgG2b
    Top Product
    Discover our top product KIR3DL1 Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: N/A, IHC: 1:200 - 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Target
    KIR3DL1 (Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 1 (KIR3DL1))
    Andere Bezeichnung
    KIR3DL1 (KIR3DL1 Produkte)
    Synonyme
    KIR3DL1 antikoerper, KIR3DL3 antikoerper, CD158E1 antikoerper, KIR antikoerper, KIR3DL1/S1 antikoerper, NKAT3 antikoerper, NKB1 antikoerper, NKB1B antikoerper, Kirl1 antikoerper, Kirl2 antikoerper, Krl1 antikoerper, killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 antikoerper, uncharacterized LOC100437736 antikoerper, killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1 antikoerper, KIR3DL1 antikoerper, LOC100437736 antikoerper, Kir3dl1 antikoerper
    Hintergrund

    Description: Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules, thus, KIR proteins are thought to play an important role in regulation of the immune response.

    Aliases: KIR, NKB1, NKAT3, NKB1B, NKAT-3, CD158E1, KIR3DL1/S1

    Molekulargewicht
    49 kDa
    Gen-ID
    3811
    HGNC
    3811
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