RGD1564516 antikoerper, MGC99322 antikoerper, TIMD4 antikoerper, B430010N18Rik antikoerper, TIM-4 antikoerper, Tim4 antikoerper, SMUCKLER antikoerper, TIM4 antikoerper, T-cell immunoglobulin and mucin domain containing 4 antikoerper, T-cell immunoglobulin and mucin domain containing 4 L homeolog antikoerper, T cell immunoglobulin and mucin domain containing 4 antikoerper, Timd4 antikoerper, TIMD4 antikoerper, timd4.L antikoerper
Hintergrund
Tim-4 is a transmembrane protein known as T cell immunoglobulin and mucin domain containing protein-4. It is expressed on antigen-presenting cells and not on T cells. Tim-4 binds to Tim-1 to promote T cell proliferation by enhancing cell division and reducing apoptosis. Tim-4 bind to phosphatidylserine through its FG-CC' binding cleft in the N-terminal IgV domain to facilitate the clearance of apoptotic cells or bodies.