GRIK1 Antikörper

Produktnummer ABIN265438

Produktdetails anti-GRIK1 Antikörper

Target: GRIK1 (Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRIK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of GluR5 protein. (region surrounding Leu12)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 1 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu GRIK1

Target: GRIK1 (Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1))

Andere Bezeichnung: Glutamate Receptor 5 / GLUR5 (GRIK1 Produkte)

Synonyme: GRIK1 antikoerper, grik1 antikoerper, fv36b03 antikoerper, wu:fv36b03 antikoerper, EAA3 antikoerper, EEA3 antikoerper, GLR5 antikoerper, GLUR5 antikoerper, GluK1 antikoerper, A830007B11Rik antikoerper, D16Ium24 antikoerper, D16Ium24e antikoerper, GluK5 antikoerper, Glur-5 antikoerper, Glur5 antikoerper, Glurbeta1 antikoerper, GluR5 antikoerper, glutamate ionotropic receptor kainate type subunit 1 antikoerper, glutamate receptor, ionotropic, kainate 1a antikoerper, glutamate receptor, ionotropic, kainate 1 antikoerper, GRIK1 antikoerper, grik1a antikoerper, Grik1 antikoerper

Hintergrund: Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamategated, caution-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem whereas the four epsilon subunits display limited distribution.Synonyms: EAA3, Excitatory amino acid receptor 3, GRIK1, Glutamate receptor ionotropic kainate 1

Molekulargewicht: approx. 100 kDa

Gen-ID: 2897

NCBI Accession: NP_000821

UniProt: P39086

Pathways: Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity