GRIK1 Antikörper (AA 10-59)
Kurzübersicht für GRIK1 Antikörper (AA 10-59) (ABIN1533290)
Target
Alle GRIK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 10-59
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Verwendungszweck
- GluR-5 Antibody
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Spezifität
- GluR-5 Polyclonal Antibody detects endogenous levels of GluR-5 protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human GluR5. AA range:10-59
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- GRIK1 (Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1))
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Andere Bezeichnung
- GluR5
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Hintergrund
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Synonyms: GRIK1; GLUR5; Glutamate receptor; ionotropic kainate 1; Excitatory amino acid receptor 3; EAA3; Glutamate receptor 5; GluR-5; GluR5
Background: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene. [provided by RefSeq, Jul 2008],
Gene Name: GRIK1
Protein Name: Glutamate receptor ionotropic kainate 1
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Molekulargewicht
- 103 kDa
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Gen-ID
- 2897
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OMIM
- 138245
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UniProt
- P39086
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Pathways
- Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity
Target
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