PPAP2A Antikörper

Produktnummer ABIN265043

Produktdetails anti-PPAP2A Antikörper

Target: PPAP2A (Phosphatidic Acid Phosphatase Type 2A (PPAP2A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPAP2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody recognizes Lysophospholipid Phosphatase (LPP) 1/1A.

Aufreinigung: Purified

Immunogen: Synthetic peptide derived from the LPP1 protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 5-10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C. Can be shipped at 2-8 °C.

Details zu PPAP2A

Target: PPAP2A (Phosphatidic Acid Phosphatase Type 2A (PPAP2A))

Andere Bezeichnung: PPAP2A / LPP1 (PPAP2A Produkte)

Synonyme: PPAP2A antikoerper, wun antikoerper, LLP1a antikoerper, LPP1 antikoerper, PAP-2a antikoerper, PAP2 antikoerper, Hic53 antikoerper, Hpic53 antikoerper, LPP-1 antikoerper, mPAP antikoerper, PAP2A antikoerper, PAP2a2 antikoerper, phospholipid phosphatase 1 antikoerper, phosphatidic acid phosphatase type 2A antikoerper, phospholipid phosphatase 1 L homeolog antikoerper, PLPP1 antikoerper, plpp1 antikoerper, Ppap2a antikoerper, plpp1.L antikoerper, Plpp1 antikoerper

Hintergrund: Broad-specificity phosphohydrolase that dephosphorylates exogenous bioactive glycerolipids and sphingolipids. Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). Pivotal regulator of lysophosphatidic acid (LPA) signaling in the cardiovascular system. Major enzyme responsible of dephosphorylating LPA in platelets, which terminates signaling actions of LPA. May control circulating, and possibly also regulate localized, LPA levels resulting from platelet activation. It has little activity towards ceramide-1-phosphate (C-1-P) and sphingosine-1-phosphate (S-1-P). The relative catalytic efficiency is LPA > PA > S-1-P > C-1-P. It's down-regulation may contribute to the development of colon adenocarcinoma.Synonyms: Lipid phosphate phosphohydrolase 1, PAP2-alpha, PAP2a, Phosphatidate phosphohydrolase type 2a, Phosphatidic acid phosphatase 2a

Gen-ID: 8611

NCBI Accession: NP_003702

UniProt: O14494

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway