CACNA1A Antikörper

Produktnummer ABIN265030

Produktdetails anti-CACNA1A Antikörper

Target: CACNA1A (Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CACNA1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Purified

Immunogen: Synthetic peptide derived from the rat alpha1A calcium channel conjugated to KLH.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 5 - 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Details zu CACNA1A

Target: CACNA1A (Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A))

Andere Bezeichnung: CACNA1A (CACNA1A Produkte)

Synonyme: cav2.1 antikoerper, cacna-a antikoerper, ca(v)2.1 antikoerper, cacna1a antikoerper, si:ch211-237k17.1 antikoerper, BccA1 antikoerper, Cav2.1 antikoerper, rbA-1 antikoerper, APCA antikoerper, BI antikoerper, CACNL1A4 antikoerper, CAV2.1 antikoerper, EA2 antikoerper, FHM antikoerper, HPCA antikoerper, MHP antikoerper, MHP1 antikoerper, SCA6 antikoerper, Caca1a antikoerper, Cacnl1a4 antikoerper, Ccha1a antikoerper, alpha1A antikoerper, la antikoerper, leaner antikoerper, nmf352 antikoerper, rkr antikoerper, rocker antikoerper, tg antikoerper, tottering antikoerper, CACH4 antikoerper, CACN3 antikoerper, calcium channel, voltage-dependent, P/Q type, alpha 1A subunit S homeolog antikoerper, calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a antikoerper, calcium voltage-gated channel subunit alpha1 A antikoerper, calcium channel, voltage-dependent, P/Q type, alpha 1A subunit antikoerper, P/Q-type voltage-gated calcium channel alpha1A subunit ChCaChA1A antikoerper, cacna1a.S antikoerper, cacna1aa antikoerper, CACNA1A antikoerper, Cacna1a antikoerper, LOC395892 antikoerper

Hintergrund: Voltage-sensitive calcium channels (VSCCs) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1a gives rise to p and/or q-type calcium currents. P/q-type calcium channels belong to the 'high-voltage activated' (hva) group and are blocked by the funnel toxin (ftx) and by the omega-agatoxin-IVA (omega-aga-IVA). They are however insensitive to dihydropyridines (dhp), and omega- conotoxin-GVIA (omega-ctx-GVIA). voltage-dependent calcium channels are multisubunit complexes, consisting of alpha-1, alpha-2, beta and delta subunits in a 1:1:1:1 ratio. The channel activity is directed by the poreforming and voltage-sensitive alpha-1 subunit. In many cases, this subunit is sufficient to generate voltage-sensitive calcium channel activity. The auxiliary subunits beta and alpha-2/delta linked by a disulfide bridge regulate the channel activity.Synonyms: Brain calcium channel I, CACH4, CACN3, CACNL1A4, Calcium channel L type alpha-1 polypeptide isoform 4, Cav2.1, Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-gated calcium channel subunit alpha

Gen-ID: 10116

UniProt: P54282

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process