KCNA1 Antikörper

Produktnummer ABIN265021

Produktdetails anti-KCNA1 Antikörper

Target: KCNA1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody reacts to Kv1.1 Potassium Channel.

Aufreinigung: Purified

Immunogen: Synthetic peptide derived from the rat Kv1.1 potassium channel conjugated to KLH.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 5 - 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Details zu KCNA1

Target: KCNA1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1))

Andere Bezeichnung: KCNA1 (KCNA1 Produkte)

Synonyme: AEMK antikoerper, EA1 antikoerper, HBK1 antikoerper, HUK1 antikoerper, KV1.1 antikoerper, MBK1 antikoerper, MK1 antikoerper, RBK1 antikoerper, KCNA1 antikoerper, AI840627 antikoerper, Kca1-1 antikoerper, Kv1.1 antikoerper, Mk-1 antikoerper, Shak antikoerper, mceph antikoerper, Kcna antikoerper, Kcpvd antikoerper, potassium voltage-gated channel subfamily A member 1 antikoerper, potassium voltage-gated channel, shaker-related subfamily, member 1 antikoerper, fragile site, aphidicolin type, common, fra(12)(q24) antikoerper, KCNA1 antikoerper, Kcna1 antikoerper, FRA12E antikoerper

Hintergrund: K+ channels from the Kv1 subfamily contain four alpha-subunits and the combinations (from Kv1.1-1.6) determine susceptibility to dendrotoxin (DTX) homologue. Kv1.1, a Shaker-like voltage-gated potassium channel, is strongly expressed in a variety of neurons in adult rodents, in which it appears to be involved in regulating neuronal excitability. Here we show that Kv1.1 is also expressed during embryonic development in the mouse, exhibiting two transient peaks of expression around embryonic day 9.5 (E9.5) and E14.5. Potassium channels play a critical role in limiting neuronal excitability. Mutations in certain voltage-gated potassium channels have been associated with hyperexcitable phenotypes in both humans and animals. However, only recently have mutations in potassium channel genes (i.e. KCNQ2 and KCNQ3) been discovered in a human epilepsy, benign familial neonatal convulsions.Synonyms: HBK1, HUKI, Potassium voltage-gated channel subfamily A member 1, Voltage-gated potassium channel subunit Kv1.1

Gen-ID: 3736

NCBI Accession: NP_000208

UniProt: Q09470