KCNA1 Produkte
(Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1))
Kategorien
This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK). [provided by RefSeq, Jul 2008].
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Ausgewählte KCNA1 Kategorien
KCNA1 Antikörper
High quality antibodies with extensive validation data.
KCNA1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene KCNA1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (2)
Kat. Nr.
ABIN7163948
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7242236
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (2)
Kat. Nr.
ABIN517306
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene KCNA1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1308384
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1308386
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN3093253
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren KCNA1 Produkten
: "N-methyl-D-aspartate receptors mediate activity-dependent down-regulation of potassium channel genes during the expression of homeostatic intrinsic plasticity." in: Molecular brain, Vol. 8, pp. 4, (2015) (PubMed).: "Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes." in: Biochimica et biophysica acta, Vol. 1854, Issue 7, pp. 827-33, (2015) (PubMed).
: "The Polarity Protein Pals1 Regulates Radial Sorting of Axons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 29, pp. 10474-84, (2015) (PubMed).
: "Expression and function of Kv1.1 potassium channels in human atria from patients with atrial fibrillation." in: Basic research in cardiology, Vol. 110, Issue 5, pp. 505, (2015) (PubMed).
: "Rapamycin reveals an mTOR-independent repression of Kv1.1 expression during epileptogenesis." in: Neurobiology of disease, Vol. 73, pp. 96-105, (2014) (PubMed).
: "Neonatal NMDA receptor blockade disrupts spike timing and glutamatergic synapses in fast spiking interneurons in a NMDA receptor hypofunction model of schizophrenia." in: PLoS ONE, Vol. 9, Issue 10, pp. e109303, (2014) (PubMed).
: "Control and plasticity of the presynaptic action potential waveform at small CNS nerve terminals." in: Neuron, Vol. 84, Issue 4, pp. 778-89, (2014) (PubMed).
: "Auditory nerve perinodal dysmyelination in noise-induced hearing loss." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 7, pp. 2684-8, (2014) (PubMed).
: "Distinct axo-somato-dendritic distributions of three potassium channels in CA1 hippocampal pyramidal cells." in: The European journal of neuroscience, Vol. 39, Issue 11, pp. 1771-83, (2014) (PubMed).
: "Kv7.2 regulates the function of peripheral sensory neurons." in: The Journal of comparative neurology, Vol. 522, Issue 14, pp. 3262-80, (2014) (PubMed).
Synonyme und alternative Namen zu KCNA1
potassium voltage-gated channel subfamily A member 1 (KCNA1), potassium voltage-gated channel, shaker-related subfamily, member 1 (KCNA1), potassium voltage-gated channel, shaker-related subfamily, member 1 (Kcna1), potassium voltage-gated channel subfamily A member 1 (Kcna1), fragile site, aphidicolin type, common, fra(12)(q24) (FRA12E), AEMK, AI840627, EA1, HBK1, HUK1, Kca1-1, Kcna, KCNA1, Kcpvd, KV1.1, Kv1.1, MBK1, mceph, Mk-1, MK1, RBK1, ShakBezeichner auf Proteinebene für KCNA1
- potassium voltage-gated channel subfamily A member 1
- voltage-gated K(+) channel HuKI
- voltage-gated potassium channel HBK1
- voltage-gated potassium channel subunit Kv1.1
- potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
- voltage-gated potassium channel Kv1.1
- potassium voltage-gated channel, shaker-related subfamily, member 1
- voltage-gated potassium channel
- potassium voltage-gated channel subfamily A member 1-like
- MKI
- brain potassium channel protein-1
- megencephaly
- potassium voltage gated channel, shaker related subfamily, member 1
- IA
- RBKI
- RCK1
- potassium (K+) channel protein voltage dependent
- potassium voltage gated channel shaker related subfamily member 1
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