VCAM1 Antikörper

Produktnummer ABIN2629808

Produktdetails anti-VCAM1 Antikörper

Target: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser VCAM1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Spezifität: Human CD106

Aufreinigung: Purified

Immunogen: B-K9 is a mouse monoclonal IgG1 antibody derived by fusion of X63/Ag8.653 mouse myeloma cells with spleen cells from BALB/c mice immunized with activated human umbilical vein endothelial cells.

Type of Immunogen: Cells

Klon: B-K9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: Flo

Usage: CD106 is a 110kD type 1 transmembrane sialoglycoprotein, which is also known as vascular cell adhesion molecule 1 (VCAM-1). The CD106 protein is primarily expressed on activated vascular endothelium but has also been detected on dendritic cell types, macrophages and non-vascular cells in certain tissues. Expression of CD106 is induced by inflammatory stimuli and cytokines. CD106 binds to the integrins CD49d/CD29 (also known as VLA4) and alpha4beta7 and is important in leucocyte-endothelial cell adhesion and signal transduction. The CD106 protein is thought to play a key role in the migration of leucocyte from the blood into tissues, particularly at sites of inflammation. Studies suggest that CD106 may also play a role in the development of rheumatoid arthritis and atherosclerosis.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C, or in small aliquots at -20°C.

Details zu VCAM1

Target: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Andere Bezeichnung: VCAM1 / CD106 (VCAM1 Produkte)

Synonyme: CD106 antikoerper, INCAM-100 antikoerper, Vcam-1 antikoerper, VCAM1B antikoerper, fi76d06 antikoerper, wu:fi76d06 antikoerper, zgc:158875 antikoerper, VCAM1 antikoerper, vascular cell adhesion molecule 1 antikoerper, vascular cell adhesion molecule 1b antikoerper, VCAM1 antikoerper, Vcam1 antikoerper, vcam1b antikoerper, VCAM-1 antikoerper

Hintergrund: Name/Gene ID: VCAM1
Family: ICAM

Synonyms: VCAM1, CD106, CD106 antigen, INCAM-100, V-CAM 1, VCAM-1

Gen-ID: 7412

Pathways: Carbohydrate Homeostasis