VCAM1 Antikörper

Produktnummer ABIN969452

Produktdetails anti-VCAM1 Antikörper

Target: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser VCAM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human VCAM1 expressed in E. coli.

Klon: 6G9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-VCAM1 Antikörper (ABIN969452)

Luo, Fang, Hsieh, Chi, Lin, Hsiao, Wu, Wang, Yang: "Involvement of MAPKs and NF-kappaB in tumor necrosis factor alpha-induced vascular cell adhesion molecule 1 expression in human rheumatoid arthritis synovial fibroblasts." in: Arthritis and rheumatism, Vol. 62, Issue 1, pp. 105-16, (2010) (PubMed).

Rubio-Guerra, Vargas-Robles, Serrano, Lozano-Nuevo, Escalante-Acosta: "Correlation between the levels of circulating adhesion molecules and atherosclerosis in type-2 diabetic normotensive patients: circulating adhesion molecules and atherosclerosis." in: Cell adhesion & migration, Vol. 3, Issue 4, pp. 369-72, (2009) (PubMed).

Details zu VCAM1

Target: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Andere Bezeichnung: VCAM1 (VCAM1 Produkte)

Synonyme: CD106 antikoerper, INCAM-100 antikoerper, Vcam-1 antikoerper, VCAM1B antikoerper, fi76d06 antikoerper, wu:fi76d06 antikoerper, zgc:158875 antikoerper, VCAM1 antikoerper, vascular cell adhesion molecule 1 antikoerper, vascular cell adhesion molecule 1b antikoerper, VCAM1 antikoerper, Vcam1 antikoerper, vcam1b antikoerper, VCAM-1 antikoerper

Hintergrund:

Description: This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.Tissue specificity: Expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue.INVITROGEN: CD106 is expressed on bone marrow stromal cells, myeloid cells, and endothelial cells.

Aliases: CD106, MGC99561, INCAM-100, DKFZp779G2333, VCAM1

Molekulargewicht: 81 kDa

Gen-ID: 7412

HGNC: 7412

Pathways: Carbohydrate Homeostasis