TRKB Antikörper (pTyr706, pTyr707)

Produktnummer ABIN2568518

Produktdetails anti-TRKB Antikörper

Target: TRKB (NTRK2) (Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))

Bindungsspezifität: pTyr706, pTyr707

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRKB Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Spezifität: The antibody detects endogenous levels of Trk B only when phosphorylated at tyrosine 706 and tyrosine 707.

Aufreinigung: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: Trk B (phospho Tyr706/Tyr707) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 706/tyrosine 707 (T-D-Y (p)-Y (p)-R-V)derived from Human Trk B.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store antibody at -20°C for up to one year.

Details zu TRKB

Target: TRKB (NTRK2) (Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))

Andere Bezeichnung: Trk B (NTRK2 Produkte)

Synonyme: trkb antikoerper, trkb-b antikoerper, xtrkb antikoerper, si:ch211-220b11.1 antikoerper, trkB2 antikoerper, NTRK2 antikoerper, ntrk2 antikoerper, gp145-trkb antikoerper, TRKB antikoerper, GP145-TrkB antikoerper, trk-B antikoerper, AI848316 antikoerper, C030027L06Rik antikoerper, Tkrb antikoerper, trkB antikoerper, RATTRKB1 antikoerper, TRKB1 antikoerper, Trk-B antikoerper, TrkB antikoerper, neurotrophic receptor tyrosine kinase 2 antikoerper, neurotrophic receptor tyrosine kinase 2 L homeolog antikoerper, neurotrophic tyrosine kinase, receptor, type 2b antikoerper, neurotrophic receptor tyrosine kinase 2 S homeolog antikoerper, neurotrophic tyrosine kinase, receptor, type 2 antikoerper, NTRK2 antikoerper, ntrk2.L antikoerper, ntrk2b antikoerper, ntrk2.S antikoerper, ntrk2 antikoerper, Ntrk2 antikoerper

Hintergrund: Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.

Molekulargewicht: 91 kDa

Gen-ID: 4915

NCBI Accession: NP_001018074

UniProt: Q16620

Pathways: RTK Signalweg, Neurotrophin Signalübertragung, cAMP Metabolic Process, Skeletal Muscle Fiber Development, Feeding Behaviour, Dicarboxylic Acid Transport