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EPOR Antikörper (pTyr368)

EPOR Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated

Produktnummer ABIN2568105

Datenblatt (PDF)

Target Alle EPOR Antikörper anzeigen

EPOR (Erythropoietin Receptor (EPOR))
Bindungsspezifität
16

11

11

8

7

7

6

5

5

5

4

3

3

3

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pTyr368
Reaktivität
120

59

49

8

5

4

3

3

2

2

2

1

1
Human, Maus, Ratte
Wirt
107

17

5

1
Kaninchen
Passende Sekundärantikörper
Klonalität
115

15
Polyklonal
Konjugat
64

15

7

5

5

4

4

4

4

4

4

4

1

1

1

1

1

1
Dieser EPOR Antikörper ist unkonjugiert
Applikation
90

46

24

23

22

15

14

14

11

5

5

5

4

2

2

1

1
Western Blotting (WB)

Spezifität

The antibody detects endogenous level of Epo-R only when phosphorylated at tyrosine 368.

Aufreinigung

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen

Epo-R (phospho Tyr368) antibody was raised against a peptide sequence around phosphorylation site of Tyrosine 368 (D-T-Y (p)-L-V) derived from Human Epo-R.

Isotyp

IgG

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EPOR Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated

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anti-Erythropoietin Receptor (EPOR) antibody
EPOR Reaktivität: Human, Maus, Ratte ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Erythropoietin Receptor (EPOR) antibody
EPOR Reaktivität: Human FACS, cELISA Wirt: Maus Monoclonal VP-2E8 unconjugated

anti-Erythropoietin Receptor (EPOR) antibody
EPOR Reaktivität: Human, Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Western Blot: 1:500~1:1000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store antibody at -20°C for up to one year.
Target

EPOR (Erythropoietin Receptor (EPOR))

Andere Bezeichnung

Epo-R (EPOR Produkte)

Synonyme

EPOR antikoerper, epor antikoerper, EPO-R antikoerper, erythropoietin receptor antikoerper, erythropoietin receptor L homeolog antikoerper, EPOR antikoerper, epor antikoerper, Epor antikoerper, epor.L antikoerper

Hintergrund

Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.

Molekulargewicht

55 kDa

Gen-ID

2057

NCBI Accession

NP_000112

UniProt

P19235

Pathways

JAK-STAT Signalweg