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CD3 epsilon Antikörper

CD3E Reaktivität: Maus FACS, WB, IHC, IF, IP, Func Wirt: Hamster Monoclonal 145-2C11 unconjugated
Produktnummer ABIN2567599
  • Target Alle CD3 epsilon (CD3E) Antikörper anzeigen
    CD3 epsilon (CD3E)
    Reaktivität
    • 201
    • 164
    • 44
    • 41
    • 18
    • 8
    • 8
    • 8
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 139
    • 105
    • 36
    • 24
    • 16
    • 10
    • 1
    Hamster
    Klonalität
    • 205
    • 120
    • 6
    Monoklonal
    Konjugat
    • 120
    • 28
    • 28
    • 18
    • 13
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD3 epsilon Antikörper ist unkonjugiert
    Applikation
    • 228
    • 154
    • 85
    • 83
    • 69
    • 66
    • 32
    • 27
    • 22
    • 19
    • 14
    • 13
    • 13
    • 13
    • 8
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Functional Studies (Func)
    Spezifität
    The 145-2C11 monoclonal antibody reacts with mouse CD3e, the 20 kDa ε chain of the TCR complex.
    Aufreinigung
    The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
    Klon
    145-2C11
    Isotyp
    IgG
    Top Product
    Discover our top product CD3E Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    2 mg/mL
    Buffer
    Phosphate-buffered aqueous solution, ph7.2.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The product should be stored undiluted at 4°C. Do not freeze.
  • Target
    CD3 epsilon (CD3E)
    Andere Bezeichnung
    CD3e (CD3E Produkte)
    Synonyme
    cd3e antikoerper, CD3E antikoerper, t3e antikoerper, tcre antikoerper, AI504783 antikoerper, CD3 antikoerper, CD3epsilon antikoerper, T3e antikoerper, T3E antikoerper, TCRE antikoerper, CD3e molecule antikoerper, CD3 antigen, epsilon polypeptide antikoerper, cd3e antikoerper, CD3E antikoerper, Cd3e antikoerper
    Hintergrund
    The 145-2C11 monoclonal antibody reacts with mouse CD3e, the 20 kDa ε chain of the TCR complex. Together with the γ and δ subunits of CD3, the ε subunits are involved in the assembly, trafficking, and surface expression of T-cell receptor complex. CD3 is expressed on thymocytes, mature T cells, and natural killer T cells, and the ε chain enhances the antigen recognition.The 145-2C11 antibody binds to the TCR complex and, depending on the conditions, initiates T cells activation, proliferation, and apoptosis. The soluble antibody seems to block lysis of target cells by antigen-specific cytotoxic T lymphocytes. The 145-2C11 antibody does not cross-react with the rat leukocytes, and it is used as a phenotypic marker for mouse T lymphocytes.
    Gen-ID
    12501
    UniProt
    P22646
    Pathways
    T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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