SAG Antikörper (pSer412)

Produktnummer ABIN2567047

Produktdetails anti-SAG Antikörper

Target: SAG (S-Antigen, Retina and Pineal Gland (Arrestin) (SAG))

Bindungsspezifität: pSer412

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SAG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: The antibody detects endogenous levels of Arrestin-1 only when phosphorylated at serine 412.

Aufreinigung: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: Arrestin 1 (phospho Ser412) antibody was raised against a peptide sequence around phosphorylation site of Serine 412 (T-G-S (p)-P-Q) derived from Human Arrestin 1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store antibody at -20°C for up to one year.

Details zu SAG

Target: SAG (S-Antigen, Retina and Pineal Gland (Arrestin) (SAG))

Andere Bezeichnung: Arrestin 1 (SAG Produkte)

Synonyme: RP47 antikoerper, S-AG antikoerper, MGC75721 antikoerper, MGC84416 antikoerper, sag antikoerper, zgc:114197 antikoerper, SAGMR antikoerper, SANTI antikoerper, ARR antikoerper, sag1 antikoerper, A930001K18Rik antikoerper, Arr1 antikoerper, Irbp antikoerper, arrestin antikoerper, S-antigen visual arrestin antikoerper, S-antigen antikoerper, S-antigen; retina and pineal gland (arrestin) antikoerper, S-antigen; retina and pineal gland (arrestin) S homeolog antikoerper, S-antigen; retina and pineal gland (arrestin) b antikoerper, S-antigen, retina and pineal gland (arrestin) antikoerper, S-antigen; retina and pineal gland (arrestin) L homeolog antikoerper, SAG antikoerper, PF10_0343 antikoerper, sag antikoerper, sag.S antikoerper, sagb antikoerper, Sag antikoerper, sag.L antikoerper

Hintergrund: Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta-arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein, the binding appears to require additional receptor determinants exposed only in the active receptor conformation.

Molekulargewicht: 50 kDa

Gen-ID: 408

NCBI Accession: NP_004032

UniProt: P49407

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling