SAG Antikörper (AA 369-418)

Produktnummer ABIN1532317

Der Kaninchen Polyklonal anti-SAG Antikörper (ABIN1532317) detektiert spezifisch SAG in WB, ELISA, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Affe.

Kurzübersicht für SAG Antikörper (AA 369-418) (ABIN1532317)

Target: SAG (S-Antigen, Retina and Pineal Gland (Arrestin) (SAG))

Reaktivität: Human, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SAG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-SAG Antikörper

Bindungsspezifität: AA 369-418

Verwendungszweck: Arrestin-β-1 Antibody

Spezifität: Arrestin-β-1 Polyclonal Antibody detects endogenous levels of Arrestin-β-1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Arrestin 1. AA range:369-418

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu SAG

Target: SAG (S-Antigen, Retina and Pineal Gland (Arrestin) (SAG))

Andere Bezeichnung: Arrestin 1

Hintergrund:

Synonyms: ARRB1, ARR1, Beta-arrestin-1, Arrestin beta-1

Background: Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011],

Gene Name: ARRB1

Protein Name: Beta-arrestin-1

Molekulargewicht: 47 kDa

Gen-ID: 408

OMIM: 107940

UniProt: P49407

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling