beta-2 Microglobulin Antikörper

Produktnummer ABIN2470504

Produktdetails anti-beta-2 Microglobulin Antikörper

Target: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser beta-2 Microglobulin Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Spezifität: Specific for human beta 2 microglobulin.B2M is the beta chain of MHC class I molecules. The precursor protein has a molecular weight of approximately 14 kDa and is 119 amino acids in length.B2M is the beta chain of MHC class I molecules. The precursor protein has a molecular weight of approximately 14 kD and is 119 amino acids in length.

Aufreinigung: Protein A Column

Immunogen: B2M monoclonal antibody was raised against highly pure B2M (Human).

Klon: 2213

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: B2M antibody can be used in ELISA, and immunohistochemistry starting at 5 μg/mL. Immunohistology: Pressure cooker antigen retrieval recommended

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 8.0, 0.05 % sodium azide, 10 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies avoid freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store B2M antibody at 4 °C or -20 °C.

Details zu beta-2 Microglobulin

Target: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Andere Bezeichnung: B2M (B2M Produkte)

Synonyme: Ly-m11 antikoerper, beta2-m antikoerper, beta2m antikoerper, bwm antikoerper, wu:fa94c05 antikoerper, wu:fb10a09 antikoerper, b2m-W01 antikoerper, b2m-W03 antikoerper, b2m-Z01 antikoerper, b2m-Z02 antikoerper, b2m-Z03 antikoerper, B2M antikoerper, b2m antikoerper, B2MG antikoerper, wu:fb66f11 antikoerper, wu:fj01f08 antikoerper, zgc:64161 antikoerper, b-2-m antikoerper, beta-2-microglobulin antikoerper, beta-2 microglobulin antikoerper, beta-2-microglobulin S homeolog antikoerper, beta-2-microglobulin, like antikoerper, B2M antikoerper, B2m antikoerper, b2m antikoerper, b2m.S antikoerper, b2ml antikoerper

Hintergrund: Beta 2-microglobulin is the low molecular weight component of HLA antigens and as such is involved in the presentation of endogenous antigens, activation of T lymphocytes and functional emergence of natural killer cells. It is found in the serum of normal individuals and in the urine in elevated amounts in patients with Wilson disease, cadmium poisoning and other conditions leading renal tubular dysfunction. ESTs have been isolated from libraries generated using virtually every tissue in the body.

Gen-ID: 567

UniProt: P61769

Pathways: T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process