SGK3 Antikörper (N-Term)

Produktnummer ABIN2469461

Produktdetails anti-SGK3 Antikörper

Target: SGK3 (serum/glucocorticoid Regulated Kinase Family, Member 3 (SGK3))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SGK3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Spezifität: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Aufreinigung: Immunoaffinity Chromatography

Immunogen: SGK3 antibody was raised against a peptide located in the N-Terminal domain of SGK3 (Human).

Anwendungsinformationen

Applikationshinweise: SGK3 antibody can be used in immunohistochemistry starting at 10 - 15 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies avoid freeze/thaw cycles.

Lagerung: 4 °C/-80 °C

Informationen zur Lagerung: SGK3 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Details zu SGK3

Target: SGK3 (serum/glucocorticoid Regulated Kinase Family, Member 3 (SGK3))

Andere Bezeichnung: SGK3 (SGK3 Produkte)

Synonyme: CISK antikoerper, SGK2 antikoerper, SGKL antikoerper, 2510015P22Rik antikoerper, A330005P07Rik antikoerper, Cisk antikoerper, fy antikoerper, fz antikoerper, Sgkl antikoerper, zgc:162253 antikoerper, serum/glucocorticoid regulated kinase family member 3 antikoerper, serum/glucocorticoid regulated kinase 3 antikoerper, serum/glucocorticoid regulated kinase family, member 3 antikoerper, serine/threonine-protein kinase Sgk3 antikoerper, SGK3 antikoerper, Sgk3 antikoerper, LOC464217 antikoerper, sgk3 antikoerper, LOC100231693 antikoerper, LOC100343709 antikoerper, LOC100052030 antikoerper, LOC100521447 antikoerper

Hintergrund: SGKL/SGK3, also known as CISK for cytokine-independent survival kinase, is a SGK type protein kinase. The protein contains a lipid-binding phox homology (PX) domain, which is required for targeting SGKL/SGK3 protein to the endosomal compartment. SGKL/SGK3 functions downstream of the phosphoinositide 3-kinase (PI3K) cascade and has been implicated in cell survival. The protein has been shown to be phosphorylated and activated by 3-phosphoinositide-dependent protein kinase 1 (PDK1), and to a lesser extent insulin-like growth factor-1, in vitro. Activated SGKL/SGK3 has been shown to phosphorylate glycogen synthase kinase 3 beta (GSK-3beta) in vitro.

Gen-ID: 23678

UniProt: Q96BR1