Endoglin Antikörper (AA 341-470)
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- Target Alle Endoglin (ENG) Antikörper anzeigen
- Endoglin (ENG)
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Bindungsspezifität
- AA 341-470
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Reaktivität
- Human
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Wirt
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Huhn
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Klonalität
- Polyklonal
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Konjugat
- Dieser Endoglin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Immunoaffinity Purified
- Top Product
- Discover our top product ENG Primärantikörper
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- Applikationshinweise
- Endoglin antibody can be used for the detection of Endoglin by Western Blot.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Phosphate-Buffered Saline. No preservatives added.
- Konservierungsmittel
- Without preservative
- Handhabung
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- ENG antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.
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- Target
- Endoglin (ENG)
- Andere Bezeichnung
- ENG (ENG Produkte)
- Synonyme
- ENG antikoerper, MGC137842 antikoerper, DKFZp469D0419 antikoerper, END antikoerper, HHT1 antikoerper, ORW1 antikoerper, AI528660 antikoerper, AI662476 antikoerper, CD105 antikoerper, S-endoglin antikoerper, endoglin antikoerper, ENG antikoerper, Eng antikoerper
- Hintergrund
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FUNCTION: Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors.
DISEASE: Defects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1) [MIM:187300], also known as Rendu-Osler-Weber syndrome 1 (ORW1). HHT1 is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations, all secondary manifestations of the underlying vascular dysplasia. Although the first symptom of HHT1 in children is generally nose bleed, there is an important clinical heterogeneity. - Molekulargewicht
- 70.6 kDa (calculated)
- Gen-ID
- 2022
- NCBI Accession
- NP_000109
- UniProt
- P17813
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