APBA1
Reaktivität: Human, Maus
WB, IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
AbBy Fluor® 488
Applikationshinweise
APBA1 antibody can be used for detection of APBA1 by ELISA at 1:62500. APBA1 antibody can be used for detection of APBA1 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Konzentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Handhabung
As with any antibody avoid repeat freeze-thaw cycles.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
For short periods of storage (days) store at 4 °C. For longer periods of storage, store APBA1 antibody at -20 °C.
Target
APBA1
(Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1))
APBA1 antikoerper, 6430513E09Rik antikoerper, Lin-10 antikoerper, Mint antikoerper, Mint1 antikoerper, Urop11 antikoerper, X11 antikoerper, X11alpha antikoerper, D9S411E antikoerper, LIN10 antikoerper, MINT1 antikoerper, X11A antikoerper, X11ALPHA antikoerper, amyloid beta precursor protein binding family A member 1 antikoerper, amyloid beta (A4) precursor protein-binding, family A, member 1b antikoerper, ketopantoate reductase antikoerper, 2-dehydropantoate 2-reductase antikoerper, amyloid beta (A4) precursor protein-binding, family A, member 1 (X11) antikoerper, amyloid beta (A4) precursor protein-binding, family A, member 1 antikoerper, amyloid beta (A4) precursor protein binding, family A, member 1 antikoerper, APBA1 antikoerper, apba1b antikoerper, apbA1 antikoerper, apba1 antikoerper, Apba1 antikoerper
Hintergrund
APBA1 is a member of the X11 protein family. It is a neuronal adaptor protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilises APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. APBA1 is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.