APBA1 Antikörper (N-Term)
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- Target Alle APBA1 Antikörper anzeigen
- APBA1 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser APBA1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- PPQQQHYVGR HQRGRALEDL RAQLGQEEEE RGECLARSAS TESGFHNHTD
- Homologie
- Human: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against APBA1. It was validated on Western Blot and immunohistochemistry.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human APBA1
- Top Product
- Discover our top product APBA1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 837 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- APBA1 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1))
- Andere Bezeichnung
- APBA1 (APBA1 Produkte)
- Synonyme
- APBA1 antikoerper, 6430513E09Rik antikoerper, Lin-10 antikoerper, Mint antikoerper, Mint1 antikoerper, Urop11 antikoerper, X11 antikoerper, X11alpha antikoerper, D9S411E antikoerper, LIN10 antikoerper, MINT1 antikoerper, X11A antikoerper, X11ALPHA antikoerper, amyloid beta precursor protein binding family A member 1 antikoerper, amyloid beta (A4) precursor protein-binding, family A, member 1b antikoerper, ketopantoate reductase antikoerper, 2-dehydropantoate 2-reductase antikoerper, amyloid beta (A4) precursor protein-binding, family A, member 1 (X11) antikoerper, amyloid beta (A4) precursor protein-binding, family A, member 1 antikoerper, amyloid beta (A4) precursor protein binding, family A, member 1 antikoerper, APBA1 antikoerper, apba1b antikoerper, apbA1 antikoerper, apba1 antikoerper, Apba1 antikoerper
- Hintergrund
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APBA1 is a member of the X11 protein family. It is a neuronal adaptor protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilises APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. APBA1 is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.
Alias Symbols: D9S411E, MINT1, X11, X11A, X11ALPHA, LIN10
Protein Interaction Partner: STXBP1, CNTNAP4, NRXN1, CNTNAP3, KIF17, LIN7B, KCNJ12, CCS, CACNA1B, HTR2C, CASK, NOTCH1, STX1A, APP, PSEN1, LIN7A, PSEN2, LIN7C, DLG1, APBB1,
Protein Size: 837 - Molekulargewicht
- 93 kDa
- Gen-ID
- 320
- NCBI Accession
- NM_001163
- UniProt
- Q02410
- Pathways
- Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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